In the ninth issue of the Bulletin of Experimental Biology and Medicine, volume 172, the article "Effects of short-term inhalations of Xe and O2 gas mixture in the rehabilitation of post-COVID ventilation failure" was published.
The article presents a theoretical rationale and a clinical case of relief of post-COVID ventilation failure with inhalation of Xe and O2 gas mixture. Pneumonitis of coronavirus etiology transforms saturated phospholipids of a surfactant into a solid-ordered phase disrupting surface tension, alveolar pneumatization and alveolar-capillary gas exchange. The molecular modeling (B3LYP/lanl2dz; GAUSSIAN09) demonstrated that due to the van der Waals dispersion interaction the Xe atom increases the distance between the acyl chains of phospholipids providing a phase transition from the solid-ordered phase to the liquid phase with the reduction of a monolayer of a surfactant surface-active film. The clinical case confirmed short-term inhalations of the Xe and O2 gas mixture relieve manifestations of ventilation insufficiency, increase SpO2 and pneumatization of the terminal parts of the lungs.
Academic Council of the Federal State Budgetary Scientific Institution "Tomsk National Research Medical Center of the Russian Academy of Sciences".
Report of the Deputy Director for Scientific and Therapeutic Work of the E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine of the Tomsk NIMC Corresponding member of the Russian Academy of Sciences, Honored Scientist of the Russian Federation V. V. Udut "New approaches to ventilation rehabilitation of patients who have suffered a coronavirus infection".
About the results obtained during the joint work of LLC "Scientific Corporation" Biology Gas Service "Yekaterinburg, Research Institute of Pharmacology and Regenerative Medicine named after E. D. Goldberg, TNIMC RAS Tomsk, LLC "Preobrazhenskaya clinic" Yekaterinburg, LLC " Medical Center "Vozrozhdenie" Kaliningrad, GKB Nakhodka Primorsky Krai, LLC Clinic of Laser Medicine "VadISmed" Nakhodka Primorsky Krai.
Union of Small and Medium-sized Businesses of the Sverdlovsk region. Conference " Rehabilitation after COVID-19. Prevention of the disease in a pandemic".
Report of the Deputy Director for Technology Development of LLC "Preobrazhenskaya Clinic" Yekaterinburg I. V. Ivanenko: "Oxygen-xenon inhalations in the rehabilitation of post-ovoid complications". The results of joint work: LLC "Preobrazhenskaya clinic" Yekaterinburg, LLC "Scientific Corporation" Biology gas Service " Yekaterinburg, Research Institute of Pharmacology and Regenerative Medicine named after E. D. Goldberg, TNIMC RAS Tomsk.
Production and sale of "Apparatus for xenon inhalation, modifications SAKI, STAKI, PAKI TU 9444-001-86202084-2010". The cost of the device of any modification is 660 thousand rubles. For more information about availability and payment terms, please contact: firstname.lastname@example.org
Pilot theoretical and experimental studies have been initiated to substantiate the treatment of adult respiratory distress syndrome using inhaled inert gases.
A study protocol was developed to evaluate the effectiveness of oxygen-xenon inhalations in the correction of astheno-vegetative post-COVID19 complications.
A clinical trial protocol has been developed for the treatment of insomnia, depression, and anxiety disorders by inhaling an oxygen-xenon mixture.
Continuation of work on improving the software for a new electronic modification of the device for xenon inhalation.
Participation in the competition "Thousand talents", China, Hangzhou
The enterprise “Scientific Corporation “BIOLOGY GAS SERVICE”, Ltd, produces “Apparatus for Xenon inhalations of modifications SAKI, STAKI and PAKI according to technical condition 9444-001-86202084-2010”. SAKI modification apparatus is designed for using under the conditions of a hospital, outpatients’ department, sanatorium, and centers of rendering palliative aid. STAKI modification apparatus is designed for using in the stomatology consulting room and outpatients’ department. PAKI modification apparatus is a portable variant and can be used in any medical-prophylaxis establishment as well as in emergency ambulances and in rendering aid outside medical institutions. The cost of the apparatus of any modification is 600 000 roubles.
For detailed information about availability and payment conditions contact: email@example.com or +7(343)777 17 25
For the production of the enterprise Certificate No 1044 was issued announcing that “STAKI” modification apparatus for Xenon inhalation was conferred the sign “Approved by StAR” of the Stomatology Association of Russia.
As result of a competition carried out by The Ministry of Industry and Science of Sverdlovsk Region the enterprise was granted the subsidy of the regional budget in 2014 for the refund connected with producing and realizing the innovative products.
“Scientific Corporation “Biology Gas Service” LLC is winner of competition hold by the State Fund of promoting the development of enterprises of smaller forms in the sphere of scientific and technical researches “Start 2-10-1”
“Scientific Corporation “Biology Gas Service” LLC is winner of competition hold by the State Fund of promoting the development of enterprises of smaller forms in the sphere of scientific and technical researches “Start 09 H2, H3” in the following directions: Medicine, Pharmacology, Biotechnology for medicine (H2) with the project “The Device for Xenon Therapy”.
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